APBA3 Protein (AA 1-138) (His tag)
-
- Target See all APBA3 Proteins
- APBA3 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-138
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This APBA3 protein is labelled with His tag.
- Purpose
- Recombinant Human Amyloid β A4 Precursor Protein-Binding A3/APBA3/X11-γ (C-6His)
- Sequence
- MDFPTISRSP SGPPAMDLEG PRDILVPSED LTPDSQWDPM PGGPGSLSRM ELDESSLQEL VQQFEALPGD LVGPSPGGAP CPLHIATGHG LASQEIADAH GLLSAEAGRD DLLGLLHCEE CPPSQTGPEE PLEPAPRLLE HHHHHH
- Characteristics
- Recombinant Human Amyloid beta A4 Precursor Protein-Binding Family A Member 3/APBA3 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu138) of Human APBA3 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product APBA3 Protein
-
Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) (AA 1-575) protein (Strep Tag)
Crystallography grade APBA3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) (AA 1-571) protein (Strep Tag)Crystallography grade APBA3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3) protein (Myc-DYKDDDDK Tag)APBA3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB ,150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
-
- Target
- APBA3 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3))
- Alternative Name
- APBA3 (APBA3 Products)
- Synonyms
- AW208791 Protein, Mint-3 Protein, X11gamma Protein, lin-10 Protein, mint3 Protein, MGC:15815 Protein, X11L2 Protein, Mint3 Protein, amyloid beta precursor protein binding family A member 3 Protein, amyloid beta (A4) precursor protein-binding, family A, member 3 Protein, APBA3 Protein, Apba3 Protein
- Sub Type
- Fusionprotein
- Background
-
Amyloid beta A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-alpha and -beta which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
Alternative Names: Amyloid Beta A4 Precursor Protein-Binding Family A Member 3, Adapter protein X11Gamma, Neuron-Specific X11L2 Protein, Neuronal Munc18-1-Interacting Protein 3, Mint-3, APBA3, MINT3, X11L2 - Molecular Weight
- 15.48kDa
- UniProt
- O96018
-
