GSTZ1 Protein (AA 1-216) (His tag)

Catalog No. ABIN1097128

Product Details

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Protein Type: Recombinant

Protein Characteristics: AA 1-216

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GSTZ1 protein is labelled with His tag.

Purpose: Recombinant Human Maleylacetoacetate Isomerase/MAA/GSTZ1 (C-6His)

Sequence: MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE EMRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRALEHH HHHH

Characteristics: Recombinant Human Maleylacetoacetate Isomerase/MAAI is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala216) of Human GSTZ1 fused with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM TrisHCl, 1 mM DTT, pH 8.0.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))

Alternative Name: Maleylacetoacetate Isomerase/MAAI (GSTZ1 Products)

Synonyms: GSTZ1-1 Protein, MAAI Protein, MAI Protein, zgc:113898 Protein, zgc:92869 Protein, PSPTO3554 Protein, DDBDRAFT_0204466 Protein, DDBDRAFT_0231608 Protein, DDB_0204466 Protein, DDB_0231608 Protein, CG9362 Protein, Dmel\CG9362 Protein, gstz1 Protein, glutathione S-transferase zeta 1 Protein, glutathione transferase zeta 1 (maleylacetoacetate isomerase) Protein, maleylacetoacetate isomerase Protein, Glutathione S transferase Z1 Protein, glutathione S-transferase zeta 1 L homeolog Protein, GSTZ1 Protein, Gstz1 Protein, gstz1 Protein, maiA Protein, hmgC Protein, Patl_1448 Protein, Pnap_2807 Protein, Bind_0562 Protein, Bphyt_0577 Protein, Dtpsy_1678 Protein, Hbal_2638 Protein, mai Protein, BC1002_0299 Protein, Fbal_2576 Protein, Mesop_3937 Protein, GstZ1 Protein, gstz1.L Protein

Sub Type: Fusionprotein

Background: Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
Alternative Names: Maleylacetoacetate Isomerase, MAAI, GSTZ1-1, Glutathione S-Transferase Zeta 1, GSTZ1

Molecular Weight: 25.18 kDa

UniProt: O43708