SERPINH1 Protein (AA 19-418) (His tag)

Catalog No. ABIN1097532

Product Details

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Protein Type: Recombinant

Protein Characteristics: AA 19-418

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This SERPINH1 protein is labelled with His tag.

Purpose: Recombinant Human Serpin H1 (C-6His)

Sequence: AEVKKPAAAA APGTAEKLSP KAATLAERSA GLAFSLYQAM AKDQAVENIL VSPVVVASSL GLVSLGGKAT TASQAKAVLS AEQLRDEEVH AGLGELLRSL SNSTARNVTW KLGSRLYGPS SVSFADDFVR SSKQHYNCEH SKINFRDKRS ALQSINEWAA QTTDGKLPEV TKDVERTDGA LLVNAMFFKP HWDEKFHHKM VDNRGFMVTR SYTVGVMMMH RTGLYNYYDD EKEKLQIVEM PLAHKLSSLI ILMPHHVEPL ERLEKLLTKE QLKIWMGKMQ KKAVAISLPK GVVEVTHDLQ KHLAGLGLTE AIDKNKADLS RMSGKKDLYL ASVFHATAFE LDTDGNPFDQ DIYGREELRS PKLFYADHPF IFLVRDTQSG SLLFIGRLVR PKGDKMRDEL VDHHHHHH

Characteristics: Recombinant Human Serpin H1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala19-Leu418) of Human SERPINH1 fused with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: Serpin-H1 (SERPINH1 Products)

Synonyms: AsTP3 Protein, CBP1 Protein, CBP2 Protein, HSP47 Protein, OI10 Protein, PPROM Protein, RA-A47 Protein, SERPINH2 Protein, gp46 Protein, SERPINH1 Protein, DKFZp468B197 Protein, cb216 Protein, hsp Protein, hsp47 Protein, id:ibd5060 Protein, wu:fc56b02 Protein, BERF-1 Protein, Cbp1 Protein, Cbp2 Protein, Hsp47 Protein, J6 Protein, Serpinh2 Protein, colligin Protein, astp3 Protein, cbp1 Protein, cbp2 Protein, pig14 Protein, pprom Protein, ra-a47 Protein, serpinh2 Protein, serpin family H member 1 Protein, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b Protein, serpin H1 Protein, selenoprotein K Protein, serine (or cysteine) peptidase inhibitor, clade H, member 1 Protein, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog Protein, SERPINH1 Protein, serpinh1b Protein, LOC100009353 Protein, Selenok Protein, Serpinh1 Protein, serpinh1.L Protein

Sub Type: Fusionprotein

Target Type: Viral Protein

Background: Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
Alternative Names: Serpin H1, 47 kDa Heat Shock Protein, Arsenic-Transactivated Protein 3, AsTP3, Cell Proliferation-Inducing Gene 14 Protein, Collagen-Binding Protein, Colligin, Rheumatoid Arthritis-Related Antigen RA-A47, SERPINH1, CBP1, CBP2, HSP47, SERPINH2

Molecular Weight: 45.5 kDa

UniProt: P50454