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SH3G2 Protein (His tag)

SH3G2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098256
  • Target See all SH3G2 Proteins
    SH3G2 (Endophilin-A1 (SH3G2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SH3G2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product SH3G2 Protein
  • Comment

    Synonyms: Endophilin-A1, CNSA2, EEN-B1, SH3D2A, SH3P4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    SH3G2 (Endophilin-A1 (SH3G2))
    Alternative Name
    SH3GL2 (SH3G2 Products)
    Synonyms
    CNSA2 Protein, EEN-B1 Protein, SH3D2A Protein, SH3P4 Protein, 9530001L19Rik Protein, AI120490 Protein, AW555077 Protein, B930049H17Rik Protein, SH3PA Protein, Sh3d2a Protein, Sh3p4 Protein, SH3 domain containing GRB2 like 2, endophilin A1 Protein, SH3-domain GRB2-like 2 Protein, SH3GL2 Protein, Sh3gl2 Protein
    Background
    SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. Recombinant human SH3GL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    42.5 kDa (376aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_003017
    Pathways
    Neurotrophin Signaling Pathway, EGFR Downregulation
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