SH3G2 Protein (His tag)
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- Target See all SH3G2 Proteins
- SH3G2 (Endophilin-A1 (SH3G2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SH3G2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SH3G2 Protein
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- Comment
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Synonyms: Endophilin-A1, CNSA2, EEN-B1, SH3D2A, SH3P4
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- SH3G2 (Endophilin-A1 (SH3G2))
- Alternative Name
- SH3GL2 (SH3G2 Products)
- Synonyms
- CNSA2 Protein, EEN-B1 Protein, SH3D2A Protein, SH3P4 Protein, 9530001L19Rik Protein, AI120490 Protein, AW555077 Protein, B930049H17Rik Protein, SH3PA Protein, Sh3d2a Protein, Sh3p4 Protein, SH3 domain containing GRB2 like 2, endophilin A1 Protein, SH3-domain GRB2-like 2 Protein, SH3GL2 Protein, Sh3gl2 Protein
- Background
- SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. Recombinant human SH3GL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 42.5 kDa (376aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_003017
- Pathways
- Neurotrophin Signaling Pathway, EGFR Downregulation
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