TCEAL7 Protein (His tag)
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- Target See all TCEAL7 Proteins
- TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TCEAL7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product TCEAL7 Protein
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- Comment
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Synonyms: Transcription elongation factor A (SII)-like 7, MPMGp800C04260Q003
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2 M NaCl, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- TCEAL7 (Transcription Elongation Factor A (SII)-Like 7 (TCEAL7))
- Alternative Name
- TCEAL7 (TCEAL7 Products)
- Synonyms
- MPMGp800C04260Q003 Protein, 1110018P05Rik Protein, transcription elongation factor A like 7 Protein, transcription elongation factor A (SII)-like 7 Protein, TCEAL7 Protein, Tceal7 Protein
- Background
- TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. Recombinant human TCEAL7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 14.8kDa(124aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_689491
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