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MED7 Protein (His tag)

MED7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN7529215
  • Target See all MED7 Proteins
    MED7 (Mediator Complex Subunit 7 (MED7))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 16
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MED7 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product MED7 Protein
  • Comment

    Synonyms: Mediator complex subunit 7, ARC34, CRSP33, CRSP9

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    MED7 (Mediator Complex Subunit 7 (MED7))
    Alternative Name
    MED7 (MED7 Products)
    Synonyms
    ARC34 Protein, CRSP33 Protein, CRSP9 Protein, 1110063B05Rik Protein, Crsp33 Protein, Crsp9 Protein, crsp9 Protein, wu:fd99d12 Protein, zgc:56241 Protein, crsp9-A Protein, med7-a Protein, mediator complex subunit 7 Protein, mediator complex subunit 7 L homeolog Protein, mediator complex subunit Protein, mediator complex subunit Med7 Protein, MED7 Protein, Med7 Protein, med7 Protein, med7.L Protein
    Background
    Mediator complex subunit 7, also known as MED7, belongs to the Mediator complex subunit 7 family. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Recombinant human MED7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    29.7 kDa (256aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_001094286
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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