PGPEP1 Protein (His tag)
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- Target See all PGPEP1 Proteins
- PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PGPEP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PGPEP1 Protein
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- Comment
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Synonyms: Pyroglutamyl-peptidase 1, Pyroglutamyl-peptidase I, Pcp, PGP, PGP-I, PGPI
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))
- Alternative Name
- PGPEP1 (PGPEP1 Products)
- Synonyms
- PGP Protein, PGP-I Protein, PGPI Protein, Pcp Protein, 2810003H13Rik Protein, Gm19458 Protein, PAP-I Protein, PAPI Protein, pyroglutamyl-peptidase I Protein, Pyroglutamyl-peptidase I Protein, Fnod_0998 Protein, Tlet_1256 Protein, Franean1_3440 Protein, Sked_37410 Protein, Arch_1014 Protein, Olsu_1567 Protein, Bcell_2984 Protein, Deima_2337 Protein, Spico_0458 Protein, Poras_1572 Protein, PGPEP1 Protein, Pgpep1 Protein
- Background
- PGPEP1 is an omega peptidase which removes pyroglutamyl residues from the amino termini of peptides and proteins. It is a cytosolic cysteine peptidase that is expressed in most cell types. The enzyme requires a thiolreducing agent for activity. PGPEP1 is potentially involved in the inactivation of biologically active peptides that possess an amino terminal pyroglutamyl group. Examples of such peptides include neurotensin, luteinizing hormone releasing hormone, and thyrotropinreleasing hormone. Recombinant human PGPEP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 25.5 kDa (232aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_060182
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