HES7 Protein (His tag)
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- Target See all HES7 Proteins
- HES7 (Hairy and Enhancer of Split 7 (HES7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HES7 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
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Hairy and Enhancer of Split 7 (HES7) (AA 1-225) protein (Strep Tag)
Crystallography grade HES7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Hairy and Enhancer of Split 7 (HES7) (AA 1-225) protein (Strep Tag)Crystallography grade HES7 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
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- Comment
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Synonyms: Transcription factor HES-7, Hairy and enhancer of split 7, bHLHb37, SCDO4
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- HES7 (Hairy and Enhancer of Split 7 (HES7))
- Alternative Name
- HES7 (HES7 Products)
- Synonyms
- SCDO4 Protein, bHLHb37 Protein, hes family bHLH transcription factor 7 Protein, hairy and enhancer of split 7 (Drosophila) Protein, HES7 Protein, Hes7 Protein
- Background
- HES7 is a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human HES7 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 27 kDa (253aa)
- NCBI Accession
- NP_001159439
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