FcRn Protein (AA 24-297) (His tag)

Catalog No. ABIN1643585

Product Details

Target: FcRn (IgG receptor FcRn (FcRn))

Protein Type: Recombinant

Protein Characteristics: AA 24-297

Origin: Cynomolgus

Source: Yeast

Purification tag / Conjugate: This FcRn protein is labelled with His tag.

Application: ELISA

Sequence: AESHLSL LYHLTAVSSP APGTPAFWVS GWLGPQQYLS YDSLRGQAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE AFKALGGKGP YTLQGLLGCE LSPDNTSVPT AKFALNGEEF MNFDLKQGTW GGDWPEALAI SQRWQQQDKA ANKELTFLLF SCPHRLREHL ERGRGNLEWK EPPSMRLKAR PGNPGFSVLT CSAFSFYPPE LQLRFLRNGM AAGTGQGDFG PNSDGSFHAS SSLTVKSGDE HHYCCIVQHA GLAQPLRVEL ETPAKSS

Specificity: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: FcRn (IgG receptor FcRn (FcRn))

Alternative Name: IgG receptor FcRn large subunit p51 (FCGRT) (FcRn Products)

Synonyms: FCRN Protein, alpha-chain Protein, FcRn Protein, Fc fragment of IgG receptor and transporter Protein, Fc receptor, IgG, alpha chain transporter Protein, FCGRT Protein, Fcgrt Protein

Background: Recommended name: IgG receptor FcRn large subunit p51.
Short name= FcRn.
Alternative name(s): IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor

UniProt: Q8SPV9

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process