Parvin alpha Protein (AA 1-372) (His tag)
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- Target See all Parvin alpha (PARVA) Proteins
- Parvin alpha (PARVA) (Parvin, alpha (PARVA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-372
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Parvin alpha protein is labelled with His tag.
- Purpose
- Recombinant Human α-Parvin/PARVA/MXRA2 (C-6His)
- Sequence
- MATSPQKSPS APKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV GERIIVKDLA EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV LEKINETLKL PPRSIKWNVD SVHAKSLVAI LHLLVALSQY FRAPIRLPDH VSIQVVVVQK REGILQSRQI QEEITGNTEA LSGRHERDAF DTLFDHAPDK LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM GLLEGYFVPL HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV LYNLFTKYRN VELEHHHHHH
- Characteristics
- Recombinant Human Alpha-Parvin/PARVA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Glu372) of Human PARVA fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PARVA Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 40 % Glycerol, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Parvin alpha (PARVA) (Parvin, alpha (PARVA))
- Alternative Name
- PARVA (PARVA Products)
- Synonyms
- CH-ILKBP Protein, MXRA2 Protein, Actp Protein, 2010012A22Rik Protein, 5430400F08Rik Protein, AI225929 Protein, AU042898 Protein, Parvin Protein, parva Protein, wu:fc59e06 Protein, zgc:101643 Protein, PARVA Protein, Parva Protein, parvin alpha Protein, parvin, alpha Protein, parvin, alpha a Protein, PARVA Protein, Parva Protein, parvaa Protein
- Sub Type
- Fusionprotein
- Background
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Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
Alternative Names: Alpha-Parvin, Actopaxin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, Matrix-Remodeling-Associated Protein 2, PARVA, MXRA2 - Molecular Weight
- 43.2 kDa
- UniProt
- Q9NVD7
- Pathways
- Smooth Muscle Cell Migration
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