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Parvin alpha Protein (AA 1-372) (His tag)

PARVA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691893
  • Target See all Parvin alpha (PARVA) Proteins
    Parvin alpha (PARVA) (Parvin, alpha (PARVA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-372
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Parvin alpha protein is labelled with His tag.
    Purpose
    Recombinant Human α-Parvin/PARVA/MXRA2 (C-6His)
    Sequence
    MATSPQKSPS APKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV GERIIVKDLA EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV LEKINETLKL PPRSIKWNVD SVHAKSLVAI LHLLVALSQY FRAPIRLPDH VSIQVVVVQK REGILQSRQI QEEITGNTEA LSGRHERDAF DTLFDHAPDK LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM GLLEGYFVPL HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV LYNLFTKYRN VELEHHHHHH
    Characteristics
    Recombinant Human Alpha-Parvin/PARVA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Glu372) of Human PARVA fused with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 50 mM Tris, 150 mM NaCl, 40 % Glycerol, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Parvin alpha (PARVA) (Parvin, alpha (PARVA))
    Alternative Name
    PARVA (PARVA Products)
    Synonyms
    CH-ILKBP Protein, MXRA2 Protein, Actp Protein, 2010012A22Rik Protein, 5430400F08Rik Protein, AI225929 Protein, AU042898 Protein, Parvin Protein, parva Protein, wu:fc59e06 Protein, zgc:101643 Protein, PARVA Protein, Parva Protein, parvin alpha Protein, parvin, alpha Protein, parvin, alpha a Protein, PARVA Protein, Parva Protein, parvaa Protein
    Sub Type
    Fusionprotein
    Background
    Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
    Alternative Names: Alpha-Parvin, Actopaxin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, Matrix-Remodeling-Associated Protein 2, PARVA, MXRA2
    Molecular Weight
    43.2 kDa
    UniProt
    Q9NVD7
    Pathways
    Smooth Muscle Cell Migration
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