SULT2A1 Protein (AA 2-285) (His tag)

Catalog No. ABIN1692213

Product Details

Target: SULT2A1 (Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))

Protein Type: Recombinant

Protein Characteristics: AA 2-285

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SULT2A1 protein is labelled with His tag.

Purpose: Recombinant Human Sulfotransferase 2A1/SULT2A1 (N-6His)

Sequence: MNHKVHHHHH HMSDDFLWFE GIAFPTMGFR SETLRKVRDE FVIRDEDVII LTYPKSGTNW LAEILCLMHS KGDAKWIQSV PIWERSPWVE SEIGYTALSE TESPRLFSSH LPIQLFPKSF FSSKAKVIYL MRNPRDVLVS GYFFWKNMKF IKKPKSWEEY FEWFCQGTVL YGSWFDHIHG WMPMREEKNF LLLSYEELKQ DTGRTIEKIC QFLGKTLEPE ELNLILKNSS FQSMKENKMS NYSLLSVDYV VDKAQLLRKG VSGDWKNHFT VAQAEDFDKL FQEKMADLPR ELFPWE

Characteristics: Recombinant Human Sulfotransferase 2A1/SULT2A1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Glu285) of Human SULT2A1 fused with a His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris, 100 mM NaCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: SULT2A1 (Sulfotransferase Family, Cytosolic, 2A, Dehydroepiandrosterone (DHEA)-Preferring, Member 1 (SULT2A1))

Alternative Name: SULT2A1 (SULT2A1 Products)

Synonyms: dhea-st Protein, dheas Protein, st2 Protein, st2a1 Protein, st2a3 Protein, sta Protein, std Protein, SULT2A1 Protein, ST2A1 Protein, Std Protein, Sth1 Protein, mSTa1 Protein, STa Protein, Smp-2 Protein, St2 Protein, St2a1 Protein, Sth2 Protein, DHEA-ST Protein, DHEAS Protein, HST Protein, ST2 Protein, ST2A3 Protein, STD Protein, hSTa Protein, sulfotransferase family 2A member 1 Protein, sulfotransferase family 2A member 1 L homeolog Protein, alcohol sulfotransferase Protein, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 Protein, SULT2A1 Protein, sult2a1.L Protein, PCC8801_2155 Protein, Cyan8802_2217 Protein, NAL212_1203 Protein, sult2a1 Protein, Sult2a1 Protein

Sub Type: Fusionprotein

Background: Bile Salt Sulfotransferase (SULT2A1( is a cytosolic enzyme that belongs to the Sulfotransferase 1 family. SULT2A1 is primarily expressed in the liver and adrenal tissues, and to a lesser extent in the kidney. SULT2A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor, and it catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. SULT2A1 may have a role in the inherited adrenal androgen excess.
Alternative Names: Bile Salt Sulfotransferase, Dehydroepiandrosterone Sulfotransferase, DHEA-ST, Hydroxysteroid Sulfotransferase, HST, ST2, ST2A3, Sulfotransferase 2A1, ST2A1, SULT2A1, HST, STD

Molecular Weight: 35.2 kDa

UniProt: Q06520

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process