SEMA4B Protein (AA 39-712) (His tag)
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- Target See all SEMA4B Proteins
- SEMA4B (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B (SEMA4B))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 39-712
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SEMA4B protein is labelled with His tag.
- Purpose
- Recombinant Human Semaphorin-4B/SEMA4B (C-6His)
- Sequence
- LSPRISLPLG SEERPFLRFE AEHISNYTAL LLSRDGRTLY VGAREALFAL SSNLSFLPGG EYQELLWGAD AEKKQQCSFK GKDPQRDCQN YIKILLPLSG SHLFTCGTAA FSPMCTYINM ENFTLARDEK GNVLLEDGKG RCPFDPNFKS TALVVDGELY TGTVSSFQGN DPAISRSQSL RPTKTESSLN WLQDPAFVAS AYIPESLGSL QGDDDKIYFF FSETGQEFEF FENTIVSRIA RICKGDEGGE RVLQQRWTSF LKAQLLCSRP DDGFPFNVLQ DVFTLSPSPQ DWRDTLFYGV FTSQWHRGTT EGSAVCVFTM KDVQRVFSGL YKEVNRETQQ WYTVTHPVPT PRPGACITNS ARERKINSSL QLPDRVLNFL KDHFLMDGQV RSRMLLLQPQ ARYQRVAVHR VPGLHHTYDV LFLGTGDGRL HKAVSVGPRV HIIEELQIFS SGQPVQNLLL DTHRGLLYAA SHSGVVQVPM ANCSLYRSCG DCLLARDPYC AWSGSSCKHV SLYQPQLATR PWIQDIEGAS AKDLCSASSV VSPSFVPTGE KPCEQVQFQP NTVNTLACPL LSNLATRLWL RNGAPVNASA SCHVLPTGDL LLVGTQQLGE FQCWSLEEGF QQLVASYCPE VVEDGVADQT DEGGSVPVII STSRVSAPAG GKASWGADRS YWKEVDHHHH HH
- Characteristics
- Recombinant Human Semaphorin-4B/SEMA4B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu39-Glu712) of Human SEMA4B fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SEMA4B Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SEMA4B (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B (SEMA4B))
- Alternative Name
- SEMA4B (SEMA4B Products)
- Synonyms
- sema4b Protein, MGC80974 Protein, SEMA4B Protein, SEMAC Protein, SemC Protein, Semac Protein, mKIAA1745 Protein, semaphorin 4B Protein, semaphorin 4B S homeolog Protein, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B Protein, SEMA4B Protein, sema4b.S Protein, Sema4b Protein
- Background
- The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.
- Molecular Weight
- 75.7 kDa
- UniProt
- Q9NPR2
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