Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL18RAP Protein (AA 20-356) (His tag)

IL18RAP Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1880623
  • Target See all IL18RAP Proteins
    IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-356
    Origin
    • 12
    • 6
    • 1
    Human
    Source
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This IL18RAP protein is labelled with His tag.
    Purpose
    Recombinant Human IL-18 Receptor Accessory Protein/IL-18RAcP/IL-1R7 (C-6His)
    Sequence
    FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKRVDH HHHHH
    Characteristics
    Recombinant Human Interleukin-18 receptor accessory protein/IL18RAP is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe20-Arg356) of Human IL18RAP fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IL18RAP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))
    Alternative Name
    Interleukin-18 Receptor Accessory Protein/IL18RAP (IL18RAP Products)
    Synonyms
    IL18RAP Protein, ACPL Protein, CD218b Protein, CDw218b Protein, IL18RB Protein, interleukin 18 receptor accessory protein Protein, IL18RAP Protein, Il18rap Protein
    Background
    IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
    Molecular Weight
    39.4 kDa
    UniProt
    O95256
You are here:
Support