ATP6V1E1 Protein (AA 1-226)

Catalog No. ABIN2468253

Product Details

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Protein Type: Recombinant

Protein Characteristics: AA 1-226

Origin: Human

Source: Escherichia coli (E. coli)

Application: ELISA, Western Blotting (WB), Mass Spectrometry (MS)

Purity: 95 %

Application Details

Application Notes: This recombinant protein can be used for WB, ELISA, MS.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM Tris, pH 8.0, 0.1 % Triton X-100, 0.002 % NaN

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Storage: -80 °C

Storage Comment: Store in working aliquots at -70 °C.

Target Details

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Alternative Name: ATP6V1E1 (ATP6V1E1 Products)

Synonyms: ATP6E Protein, ATP6E2 Protein, ATP6V1E Protein, P31 Protein, Vma4 Protein, 2410029D23Rik Protein, Atp6e Protein, Atp6e2 Protein, Atp6v1e Protein, D6Ertd385e Protein, E2 Protein, T22B4.130 Protein, T22B4_130 Protein, TUFF Protein, V-ATPase subunit E1 Protein, VACUOLAR H+-ATPASE SUBUNIT E ISOFORM 1 Protein, VHA-E1 Protein, emb2448 Protein, embryo defective 2448 Protein, vacuolar ATP synthase subunit E1 Protein, atp6e Protein, atp6v1e1 Protein, chunp6932 Protein, fj35f08 Protein, wu:fj35f08 Protein, ATPase H+ transporting V1 subunit E1 Protein, ATPase, H+ transporting, lysosomal V1 subunit E1 Protein, vacuolar ATP synthase subunit E1 Protein, ATPase, H+ transporting, lysosomal, V1 subunit E1b Protein, ATP6V1E1 Protein, Atp6v1e1 Protein, atp6v1e1 Protein, TUF Protein, atp6v1e1b Protein

Background: This protein is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It contains the ATP catalytic site. The protein is known as the E subunit and is found ubiquitously.

Molecular Weight: 26 kDa (Calculated)

Gene ID: 529

NCBI Accession: NP_001687

OMIM: 4502317

UniProt: P36543

Pathways: Transition Metal Ion Homeostasis, Proton Transport