PSMC6 Protein (AA 1-389)
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- Target See all PSMC6 Proteins
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-389
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Western Blotting (WB), ELISA, Mass Spectrometry (MS)
- Purity
- 95 %
- Top Product
- Discover our top product PSMC6 Protein
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- Application Notes
- This recombinant protein can be used for WB, ELISA, MS.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM Tris, pH 8.0, 0.1 % Triton X-100, 0.002 % NaN
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -80 °C
- Storage Comment
- Store in working aliquots at -70 °C.
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- Target
- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
- Alternative Name
- PSMC6 (PSMC6 Products)
- Synonyms
- DDBDRAFT_0186051 Protein, DDBDRAFT_0232968 Protein, DDB_0186051 Protein, DDB_0232968 Protein, fb20g04 Protein, wu:fb20g04 Protein, wu:fc85c10 Protein, cadp44 Protein, sug2 Protein, PSMC6 Protein, psmc6-a Protein, NV13405 Protein, CADP44 Protein, P44 Protein, SUG2 Protein, p42 Protein, 2300001E01Rik Protein, AI451058 Protein, 26S protease regulatory subunit S10B Protein, 26S proteasome regulatory subunit 10B Protein, proteasome 26S subunit, ATPase 6 Protein, proteasome 26S subunit, ATPase 6 L homeolog Protein, 26S protease regulatory subunit 10B Protein, proteasome 26S subunit, ATPase 6 S homeolog Protein, proteasome (prosome, macropain) 26S subunit, ATPase, 6 Protein, ATEG_02903 Protein, HCAG_04181 Protein, LOC5565051 Protein, EDI_289460 Protein, CpipJ_CPIJ003334 Protein, EHI_194070 Protein, PTRG_02716 Protein, BDBG_01801 Protein, psmC6 Protein, MCYG_07206 Protein, PITG_00229 Protein, VDBG_04729 Protein, MGYG_04704 Protein, TERG_01608 Protein, DICPUDRAFT_97252 Protein, Tsp_02519 Protein, prs10 Protein, LOC100282100 Protein, Psmc6 Protein, psmc6 Protein, psmc6.L Protein, PSMC6 Protein, LOC693577 Protein, psmc6.S Protein, LOC100117671 Protein
- Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits , 2 rings are composed of 7 α subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
- Molecular Weight
- 44.7 kDa (Calculated)
- Gene ID
- 5706
- NCBI Accession
- NP_002797
- OMIM
- 24430160
- UniProt
- P62333
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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