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IL18BP Protein (Fc Tag)

IL18BP Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Catalog No. ABIN2566702
  • Target See all IL18BP Proteins
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    Protein Type
    Recombinant
    Origin
    • 13
    • 6
    • 3
    • 2
    • 1
    Human
    Source
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL18BP protein is labelled with Fc Tag.
    Application
    Western Blotting (WB)
    Characteristics

    Fusion tag: C-Fc Tag

    Purity
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product IL18BP Protein
  • Application Notes
    This recombinant protein can be used for WB. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM tris, 100 mM glycine, pH 7.5
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    IL18BP (Interleukin 18 Binding Protein (IL18BP))
    Alternative Name
    IL18 BP (IL18BP Products)
    Synonyms
    IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
    Background
    Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
    Molecular Weight
    44.3 kDa
    Gene ID
    10068
    NCBI Accession
    NP_001138529
    UniProt
    O95998
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