IL18BP Protein (Fc Tag)
-
- Target See all IL18BP Proteins
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL18BP protein is labelled with Fc Tag.
- Application
- Western Blotting (WB)
- Characteristics
-
Fusion tag: C-Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product IL18BP Protein
-
-
- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 50 mM tris, 100 mM glycine, pH 7.5
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
-
- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Alternative Name
- IL18 BP (IL18BP Products)
- Synonyms
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Background
- Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
- Molecular Weight
- 44.3 kDa
- Gene ID
- 10068
- NCBI Accession
- NP_001138529
- UniProt
- O95998
-