LRRC4 Protein (His tag)
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- Target See all LRRC4 Proteins
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRRC4 protein is labelled with His tag.
- Application
- ELISA, Western Blotting (WB)
- Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized Recombinant mouse Netrin-G2a Fc chimera at 4 μg/mL, can bind rhLRRC4 with an apparent KD < 10 nM.
- Purity
- >92 % as determined by SDS-PAGE.
- Top Product
- Discover our top product LRRC4 Protein
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Leucine Rich Repeat Containing 4 (LRRC4) (AA 549-653) protein (His tag)
Crystallography grade LRRC4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 548-652) protein (His tag)Crystallography grade LRRC4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-527) protein (His tag)Crystallography grade LRRC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 41-526) protein (His tag)Crystallography grade LRRC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-653) protein (rho-1D4 tag)Crystallography grade LRRC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 41-652) protein (rho-1D4 tag)Crystallography grade LRRC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-527) protein (His tag)LRRC4 Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
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- Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Alternative Name
- NGL 2 (LRRC4 Products)
- Synonyms
- NGL-2 Protein, MBAG1 Protein, NLG-2 Protein, Nag14 Protein, leucine rich repeat containing 4 Protein, LRRC4 Protein, Lrrc4 Protein
- Background
- LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
- Molecular Weight
- 55.6 kDa
- Gene ID
- 64101
- UniProt
- Q9HBW1
- Pathways
- Synaptic Membrane
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