ITGB1BP1 Protein (His tag)

Catalog No. ABIN2712305

Product Details

Target: ITGB1BP1 (Integrin beta 1 Binding Protein 1 (ITGB1BP1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ITGB1BP1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ITGB1BP1 / ICAP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 100 mM Arg. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ITGB1BP1 (Integrin beta 1 Binding Protein 1 (ITGB1BP1))

Alternative Name: Itgb1bp1,icap1 (ITGB1BP1 Products)

Synonyms: si:dkey-27p7.1 Protein, zgc:123198 Protein, ICAP-1A Protein, ICAP-1B Protein, ICAP-1alpha Protein, ICAP1 Protein, ICAP1A Protein, ICAP1B Protein, AI449260 Protein, AU019480 Protein, Icap1 Protein, integrin subunit beta 1 binding protein 1 Protein, integrin beta 1 binding protein 1 Protein, Itgb1bp1 Protein, itgb1bp1 Protein, ITGB1BP1 Protein

Background: The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

Molecular Weight: 21.8 kDa

NCBI Accession: NP_004754

Pathways: Tube Formation