ASCC1 Protein (Myc-DYKDDDDK Tag)
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- Target See all ASCC1 Proteins
- ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ASCC1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Activating signal cointegrator 1 complex subunit 1 (ASCC1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ASCC1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
- Abstract
- ASCC1 Products
- Synonyms
- ASC1p50 Protein, p50 Protein, Asc-1 Protein, CGI-18 Protein, 1810015P09Rik Protein, AI550520 Protein, activating signal cointegrator 1 complex subunit 1 Protein, ascc1 Protein, ASCC1 Protein, Ascc1 Protein
- Background
- This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
- Molecular Weight
- 41 kDa
- NCBI Accession
- NP_057031
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