ANAPC2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714781

Product Details

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ANAPC2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human APC2 / ANAPC2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Alternative Name: Apc2,anapc2 (ANAPC2 Products)

Synonyms: anapc2 Protein, ANAPC2 Protein, DDBDRAFT_0203816 Protein, DDBDRAFT_0234264 Protein, DDB_0203816 Protein, DDB_0234264 Protein, si:ch73-203i15.5 Protein, APC2 Protein, RP11-350O14.5 Protein, 9230107K09Rik Protein, AL024279 Protein, Apc2 Protein, Emi4 Protein, Imi4 Protein, mKIAA1406 Protein, F28I8.30 Protein, F28I8_30 Protein, anaphase-promoting complex/cyclosome 2 Protein, anaphase promoting complex subunit 2 Protein, anaphase promoting complex subunit 2 L homeolog Protein, anaphase-promoting complex/cyclosome 2 Protein, Anaphase-promoting complex subunit 2 Protein, ANAPC2 Protein, anapc2.L Protein, anapc2 Protein, Anapc2 Protein, APC2 Protein, apc-2 Protein

Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Molecular Weight: 93.6 kDa

NCBI Accession: NP_037498

Pathways: Regulation of Cell Size