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ATP7B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ATP7B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715066
  • Target See all ATP7B Proteins
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 6
    • 5
    Human
    Source
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ATP7B protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ATP7B (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATP7B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Alternative Name
    Atp7b (ATP7B Products)
    Synonyms
    PWD Protein, WC1 Protein, WD Protein, WND Protein, Atp7a Protein, tx Protein, Hts Protein, PINA Protein, Wd Protein, ATP7B Protein, ATPase copper transporting beta Protein, ATPase, Cu++ transporting, beta polypeptide Protein, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) Protein, copper-transporting ATPase 2 Protein, ATP7B Protein, Atp7b Protein, atp7b Protein, LOC592143 Protein
    Background
    This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
    Molecular Weight
    157.1 kDa
    NCBI Accession
    NP_000044
    Pathways
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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