DCLK2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all DCLK2 Proteins
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DCLK2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Doublecortin-like kinase 2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DCLK2 Protein
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Doublecortin-Like Kinase 2 (DCLK2) (AA 1-695) (Active) protein (GST tag)
DCLK2 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Doublecortin-Like Kinase 2 (DCLK2) (AA 1-766) protein (Strep Tag)Crystallography grade DCLK2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Doublecortin-Like Kinase 2 (DCLK2) (AA 1-756) protein (Strep Tag)Crystallography grade DCLK2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
- Alternative Name
- Doublecortin-Like Kinase 2 (DCLK2 Products)
- Synonyms
- CL2 Protein, CLICK-II Protein, CLICK2 Protein, CLIK2 Protein, DCAMKL2 Protein, DCDC3 Protein, DCDC3B Protein, DCK2 Protein, 6330415M09Rik Protein, AU044875 Protein, Click-II Protein, Dcamkl2 Protein, DCLK2 Protein, cb572 Protein, dclk Protein, sb:cb572 Protein, si:dkey-180n16.1 Protein, Dck2 Protein, RGD1308384 Protein, doublecortin like kinase 2 Protein, doublecortin-like kinase 2 Protein, doublecortin-like kinase 2a Protein, DCLK2 Protein, Dclk2 Protein, dclk2a Protein
- Background
- This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
- Molecular Weight
- 83.4 kDa
- NCBI Accession
- NP_001035350
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