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DCTN3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Dctn3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719849
  • Target See all DCTN3 (Dctn3) Proteins
    DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DCTN3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Dynactin subunit 3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product Dctn3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
    Alternative Name
    Dynactin Subunit 3 (Dctn3 Products)
    Synonyms
    zgc:92471 Protein, wu:fc38g10 Protein, p24 Protein, NV12799 Protein, DCTN-22 Protein, DCTN22 Protein, dynactin 3 (p22) Protein, dynactin subunit 3 Protein, dynactin 3 Protein, dctn3 Protein, LOC658790 Protein, Dctn3 Protein, DCTN3 Protein
    Background
    This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    20.9 kDa
    NCBI Accession
    NP_009165
    Pathways
    M Phase
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