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FOXP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FOXP3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721384
  • Target See all FOXP3 Proteins
    FOXP3 (Forkhead Box P3 (FOXP3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FOXP3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human FOXP3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FOXP3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: "Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).

  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Alternative Name
    Foxp3 (FOXP3 Products)
    Synonyms
    foxp3 Protein, FOXP3 Protein, AIID Protein, DIETER Protein, IPEX Protein, PIDX Protein, XPID Protein, JM2 Protein, scurfin Protein, sf Protein, RGD1562112 Protein, forkhead box P3 Protein, forkhead box P3a Protein, forkhead box P3 L homeolog Protein, FOXP3 Protein, foxp3a Protein, foxp3 Protein, foxp3.L Protein, Foxp3 Protein
    Background
    The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Molecular Weight
    47.1 kDa
    NCBI Accession
    NP_054728
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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