GMDS Protein (Myc-DYKDDDDK Tag)
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- Target See all GMDS Proteins
- GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GMDS protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GMDS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GMDS Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))
- Alternative Name
- Gmds (GMDS Products)
- Synonyms
- BC031788 Protein, C87208 Protein, GMD Protein, SDR3E1 Protein, GDP-mannose 4, 6-dehydratase Protein, GDP-mannose 4,6-dehydratase Protein, Gmds Protein, GMDS Protein
- Background
- GDP-mannose 4,6-dehydratase (GMD EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009].
- Molecular Weight
- 41.8 kDa
- NCBI Accession
- NP_001491
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