GPSM2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722203

Product Details

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GPSM2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human GPSM2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Alternative Name: Gpsm2 (GPSM2 Products)

Synonyms: CMCS Protein, DFNB82 Protein, LGN Protein, PINS Protein, dfnb82 Protein, lgn Protein, pins Protein, RGD1560967 Protein, Pinsa Protein, zgc:63574 Protein, 6230410J09Rik Protein, Pins Protein, G protein signaling modulator 2 Protein, G-protein signaling modulator 2 S homeolog Protein, G-protein signaling modulator 2 Protein, G-protein signalling modulator 2 (AGS3-like, C. elegans) Protein, GPSM2 Protein, gpsm2.S Protein, Gpsm2 Protein, gpsm2 Protein

Background: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants.

Molecular Weight: 76.5 kDa

NCBI Accession: NP_037428

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling