HNRNPA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722904

Product Details

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HNRNPA1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human hnRNP core protein A1 / HNRNPA1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Zheng, Worthington, Timms, Woo: "HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription." in: Genes and immunity, Vol. 14, Issue 8, pp. 479-86, (2013) (PubMed).

Target Details

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Alternative Name: Hnrnp Core Protein a1,hnrnpa1 (HNRNPA1 Products)

Synonyms: HNRPA1 Protein, HNRPA1L3 Protein, hnRNP A1 Protein, hnRNP-A1 Protein, hnrpa1 Protein, TPT1P Protein, HNRNPA1 Protein, D15Ertd119e Protein, Hdp Protein, Hnrpa1 Protein, hnrnp-A1 Protein, ROA1 Protein, zgc:66127 Protein, heterogeneous nuclear ribonucleoprotein A1 Protein, heterogeneous nuclear ribonucleoprotein A1b Protein, Heterogeneous nuclear ribonucleoprotein A1 Protein, heterogeneous nuclear ribonucleoprotein A1 S homeolog Protein, ribonucleoprotein A1a Protein, heterogeneous nuclear ribonucleoprotein A1-like Protein, heterogeneous nuclear ribonucleoprotein A1a Protein, HNRNPA1 Protein, hnrnpa1b Protein, LOC100101226 Protein, roa1 Protein, Hnrnpa1 Protein, hnrnpa1.S Protein, hnrnpa1 Protein, LOC100359118 Protein, hnrnpa1a Protein

Background: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Molecular Weight: 34 kDa

NCBI Accession: NP_002127