HSCB Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723069

Product Details

Target: HSCB (HscB Iron-Sulfur Cluster Co-Chaperone Homolog (HSCB))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HSCB protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human HSCB / DNAJC20 / HSC20 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HSCB (HscB Iron-Sulfur Cluster Co-Chaperone Homolog (HSCB))

Alternative Name: Hscb,dnajc20,hsc20 (HSCB Products)

Synonyms: RGD1311005 Protein, DNAJC20 Protein, HSC20 Protein, JAC1 Protein, dJ366L4.2 Protein, AI325508 Protein, AW049829 Protein, Hsc20 Protein, HscB mitochondrial iron-sulfur cluster co-chaperone Protein, HscB mitochondrial iron-sulfur cluster cochaperone Protein, HscB iron-sulfur cluster co-chaperone Protein, Hscb Protein, HSCB Protein

Background: This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.

Molecular Weight: 27.2 kDa

NCBI Accession: NP_741999