IL-19 Protein (Transcript Variant 2)
-
- Target See all IL-19 (IL19) Proteins
- IL-19 (IL19) (Interleukin 19 (IL19))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 2
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
-
- Recombinant human Interleukin-19 / IL19 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to activate STAT following receptor-ligand interaction.
- Top Product
- Discover our top product IL19 Protein
-
Interleukin 19 (IL19) (AA 25-177) protein (Fc Tag)
IL19 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 19 (IL19) (AA 25-176) protein (His tag)IL19 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 19 (IL19) (AA 1-215) protein (GST tag)IL19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 19 (IL19) (AA 57-156) protein (GST tag)IL19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 19 (IL19) (AA 25-177) protein (His tag)Crystallography grade IL19 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 19 (IL19) (AA 25-176) protein (His tag)Crystallography grade IL19 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
-
- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- IL-19 (IL19) (Interleukin 19 (IL19))
- Alternative Name
- Interleukin-19,il19 (IL19 Products)
- Synonyms
- IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
- Background
- The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
- Molecular Weight
- 17.9 kDa
- NCBI Accession
- NP_037503
-
