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ICA1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ICA1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723824
  • Target See all ICA1 Proteins
    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ICA1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Islet cell autoantigen 1 / ICA1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ICA1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ICA1 (Islet Cell Autoantigen 1, 69kDa (ICA1))
    Alternative Name
    Islet Cell Autoantigen 1,ica1 (ICA1 Products)
    Synonyms
    ica1 Protein, MGC52730 Protein, ICA1 Protein, DKFZp469G0321 Protein, zgc:92566 Protein, 69kDa Protein, ICA69 Protein, Ica69 Protein, MGC83241 Protein, ICAp69 Protein, islet cell autoantigen 1 L homeolog Protein, islet cell autoantigen 1 Protein, Islet cell autoantigen 1 Protein, islet cell autoantigen 1 S homeolog Protein, ica1.L Protein, ICA1 Protein, ica1 Protein, ica69 Protein, Ica1 Protein, ica1.S Protein
    Background
    This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren&aposs syndrome. Several transcript variants encoding two different isoforms have been found for this gene.
    Molecular Weight
    54.5 kDa
    NCBI Accession
    NP_004959
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