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FN3KRP Protein (Myc-DYKDDDDK Tag)

FN3KRP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724151
  • Target See all FN3KRP Proteins
    FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FN3KRP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Ketosamine-3-kinase protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FN3KRP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FN3KRP (Fructosamine 3 Kinase Related Protein (FN3KRP))
    Alternative Name
    Ketosamine-3-Kinase (FN3KRP Products)
    Synonyms
    FN3KL Protein, FN3K-RP Protein, fn3k Protein, fn3kl Protein, MGC145992 Protein, DKFZP469K211 Protein, RGD1304570 Protein, zgc:101634 Protein, fructosamine 3 kinase related protein Protein, fructosamine-3-kinase-related protein Protein, FN3KRP Protein, Fn3krp Protein, fn3krp Protein
    Background
    A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    34.2 kDa
    NCBI Accession
    NP_078895
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