LRWD1 Protein (Myc-DYKDDDDK Tag)
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- Target See all LRWD1 Proteins
- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRWD1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human LRWD1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LRWD1 Protein
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Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 1-647) protein (Strep Tag)
Crystallography grade LRWD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 1-648) protein (Strep Tag)Crystallography grade LRWD1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
- Alternative Name
- Lrwd1 (LRWD1 Products)
- Synonyms
- CENP-33 Protein, ORCA Protein, 1200011O22Rik Protein, AU042569 Protein, AW548074 Protein, Orca Protein, si:dkey-261j4.9 Protein, wu:fb78b03 Protein, wu:ft31b04 Protein, leucine rich repeats and WD repeat domain containing 1 Protein, leucine-rich repeats and WD repeat domain containing 1 Protein, microRNA 5090 Protein, leucine-rich repeats and WD repeat domain containing 1 L homeolog Protein, LRWD1 Protein, Lrwd1 Protein, lrwd1 Protein, MIR5090 Protein, lrwd1.L Protein
- Background
- The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 70.7 kDa
- NCBI Accession
- NP_690852
- Pathways
- Chromatin Binding
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