NCOA4 Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726904

Product Details

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 5

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This NCOA4 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NCoA-4 (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: Ncoa-4 (NCOA4 Products)

Synonyms: zgc:55307 Protein, zgc:77270 Protein, NCOA4 Protein, MGC138109 Protein, rfg Protein, ele1 Protein, ptc3 Protein, ara70 Protein, MGC84996 Protein, DKFZp469A035 Protein, DKFZp459B2429 Protein, DKFZp469A1925 Protein, ncoa4 Protein, ARA70 Protein, ELE1 Protein, PTC3 Protein, RFG Protein, 1110034E15Rik Protein, 4432406M01Rik Protein, AI227008 Protein, Rfg Protein, nuclear receptor coactivator 4 Protein, nuclear receptor coactivator 4 S homeolog Protein, Ncoa4 Protein, ncoa4 Protein, NCOA4 Protein, ncoa4.S Protein

Background: This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Molecular Weight: 69.5 kDa

NCBI Accession: NP_005428

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway