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NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

NECAB3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727054
  • Target See all NECAB3 Proteins
    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 2
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This NECAB3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human NECAB3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NECAB3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
    Alternative Name
    Necab3 (NECAB3 Products)
    Synonyms
    Apba2bp Protein, APBA2BP Protein, NECAB3 Protein, EFCBP3 Protein, NIP1 Protein, STIP3 Protein, SYTIP2 Protein, XB51 Protein, dJ63M2.4 Protein, dJ63M2.5 Protein, 2900010M17Rik Protein, AI853434 Protein, Nip1 Protein, N-terminal EF-hand calcium binding protein 3 Protein, Necab3 Protein, NECAB3 Protein
    Background
    The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    40.6 kDa
    NCBI Accession
    NP_112508
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