NOS1AP Protein (His tag)

Catalog No. ABIN2727469

Product Details

Target: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NOS1AP protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NOS1AP (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Alternative Name: Nos1ap (NOS1AP Products)

Synonyms: MGC78853 Protein, Capon Protein, MGC145362 Protein, 6330408P19Rik Protein, CAPON Protein, nitric oxide synthase 1 adaptor protein Protein, nitric oxide synthase 1 adaptor protein L homeolog Protein, nitric oxide synthase 1 (neuronal) adaptor protein a Protein, carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein Protein, chromosome 18 C1orf226 homolog Protein, nitric oxide synthase 1 (neuronal) adaptor protein Protein, NOS1AP Protein, nos1ap.L Protein, nos1apa Protein, LOC609484 Protein, nos1ap Protein, LOC100058633 Protein, C18H1orf226 Protein, Nos1ap Protein

Background: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 56 kDa

NCBI Accession: NP_055512