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OCRL Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

OCRL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727867
  • Target See all OCRL Proteins
    OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant A
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This OCRL protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human OCRL (transcript variant a) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product OCRL Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
    Alternative Name
    Ocrl (OCRL Products)
    Synonyms
    OCRL Protein, wu:fi09g03 Protein, zgc:152864 Protein, locr Protein, nphl2 Protein, ocrl1 Protein, inpp5f Protein, INPP5F Protein, LOCR Protein, NPHL2 Protein, OCRL-1 Protein, OCRL1 Protein, 9530014D17Rik Protein, BB143339 Protein, OCRL, inositol polyphosphate-5-phosphatase Protein, phosphatidylinositol polyphosphate 5-phosphatase Protein, oculocerebrorenal syndrome of Lowe Protein, Ocrl Protein, NAEGRDRAFT_58601 Protein, OCRL Protein, ocrl Protein
    Background
    This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
    Molecular Weight
    104 kDa
    NCBI Accession
    NP_000267
    Pathways
    Inositol Metabolic Process
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