OPTN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all OPTN Proteins
- OPTN (Optineurin (OPTN))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OPTN protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Optineurin / HIP7 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product OPTN Protein
-
Optineurin (OPTN) (AA 16-223) protein (His-IF2DI Tag)
OPTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Optineurin (OPTN) (AA 1-571) protein (GST tag)OPTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Optineurin (OPTN) (AA 1-577) protein (GST tag)OPTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Optineurin (OPTN) (AA 1-577) protein (Strep Tag)Crystallography grade OPTN Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Optineurin (OPTN) (AA 1-584) protein (Strep Tag)Crystallography grade OPTN Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- OPTN (Optineurin (OPTN))
- Alternative Name
- Optineurin,hip7 (OPTN Products)
- Synonyms
- nrp Protein, fip2 Protein, hip7 Protein, hypl Protein, glc1e Protein, tfiiia-intp Protein, ALS12 Protein, FIP2 Protein, GLC1E Protein, HIP7 Protein, HYPL Protein, NRP Protein, TFIIIA-INTP Protein, Fip2 Protein, 4930441O07Rik Protein, fj52f04 Protein, si:ch211-240l19.3 Protein, wu:fj52f04 Protein, zgc:66386 Protein, zgc:77868 Protein, optineurin Protein, optineurin L homeolog Protein, OPTN Protein, optn Protein, Optn Protein, optn.L Protein
- Background
- This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
- Molecular Weight
- 65.7 kDa
- NCBI Accession
- NP_001008212
- Pathways
- M Phase
-
