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Osteocalcin Protein (BGLAP) (Myc-DYKDDDDK Tag)

BGLAP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728008
  • Target See all Osteocalcin (BGLAP) Proteins
    Osteocalcin (BGLAP)
    Protein Type
    Recombinant
    Origin
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 25
    • 18
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Osteocalcin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Osteocalcin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BGLAP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Osteocalcin (BGLAP)
    Alternative Name
    Osteocalcin (BGLAP Products)
    Synonyms
    BGP Protein, OC Protein, OCN Protein, Bglap1 Protein, Bglap2 Protein, OG1 Protein, mOC-A Protein, Bgp Protein, Bgpr Protein, Bgpra Protein, bgp Protein, LOC792433 Protein, ocn Protein, GLA Protein, BGLAP Protein, PMF1 Protein, bone gamma-carboxyglutamate protein Protein, bone gamma carboxyglutamate protein Protein, bone gamma-carboxyglutamate protein S homeolog Protein, bone gamma-carboxyglutamate (gla) protein Protein, osteocalcin Protein, polyamine-modulated factor 1 Protein, BGLAP Protein, Bglap Protein, bglap.S Protein, bglap Protein, ocn Protein, LOC100529177 Protein, LOC100146589 Protein
    Background
    This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
    Molecular Weight
    8.7 kDa
    NCBI Accession
    NP_954642
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