PKN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PKN1 Proteins
- PKN1 (Protein Kinase N1 (PKN1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PKN1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PKN1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PKN1 Protein
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Protein Kinase N1 (PKN1) (AA 1-942) (Active) protein (GST tag)
PKN1 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Protein Kinase N1 (PKN1) (AA 1-942) (Active) protein (His-GST)PKN1 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Protein Kinase N1 (PKN1) (AA 1-942) protein (GST tag)PKN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase N1 (PKN1) (AA 462-615) protein (GST tag)PKN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Kinase N1 (PKN1) (AA 2-942) protein (His tag)Crystallography grade PKN1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Protein Kinase N1 (PKN1) (AA 2-946) protein (His tag)Crystallography grade PKN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PKN1 (Protein Kinase N1 (PKN1))
- Alternative Name
- Pkn1 (PKN1 Products)
- Synonyms
- DBK Protein, PAK-1 Protein, PAK1 Protein, PKN Protein, PKN-ALPHA Protein, PRK1 Protein, PRKCL1 Protein, F730027O18Rik Protein, Pkn Protein, Prkcl1 Protein, Stk3 Protein, PKN1 Protein, 3-2 Protein, CG2049 Protein, CG2055 Protein, CT6637 Protein, CT6660 Protein, DPKN Protein, Dmel\\CG2049 Protein, Dpkn Protein, PRK2 Protein, Pk45C Protein, Pk?3 Protein, dPKN Protein, l(2)06736 Protein, l(2)45Ca Protein, v(2)rG232 Protein, protein kinase N1 Protein, protein kinase N1b Protein, Protein kinase N Protein, PKN1 Protein, Pkn1 Protein, pkn1b Protein, pkn1 Protein, Pkn Protein
- Background
- The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molecular Weight
- 103.8 kDa
- NCBI Accession
- NP_002732
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