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PLA2G12B Protein (Myc-DYKDDDDK Tag)

PLA2G12B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729072
  • Target See all PLA2G12B Proteins
    PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PLA2G12B protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PLA2G12B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PLA2G12B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))
    Alternative Name
    Pla2g12b (PLA2G12B Products)
    Synonyms
    wu:fb26d02 Protein, wu:fb99g06 Protein, wu:fc91d12 Protein, zgc:111897 Protein, zgc:56487 Protein, zgc:77746 Protein, MGC79728 Protein, GXIIB Protein, GXIIIsPLA2 Protein, PLA2G13 Protein, 2010002E04Rik Protein, Pla2g13 Protein, hlb218 Protein, phospholipase A2, group XIIB Protein, phospholipase A2 group XIIB Protein, pla2g12b Protein, PLA2G12B Protein, Pla2g12b Protein
    Background
    The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants.
    Molecular Weight
    21.5 kDa
    NCBI Accession
    NP_115951
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