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LCP1 Protein (Myc-DYKDDDDK Tag)

LCP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729119
  • Target See all LCP1 Proteins
    LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This LCP1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Plastin 2 / LCP1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LCP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Dubey, Singh, Awasthi, Nagarkoti, Kumar, Ali, Chandra, Kumar, Barthwal, Jagavelu, Sánchez-Gómez, Lamas, Dikshit: "L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions." in: Free radical biology & medicine, Vol. 86, pp. 1-15, (2015) (PubMed).

  • Target
    LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))
    Alternative Name
    Plastin 2,lcp1 (LCP1 Products)
    Synonyms
    CP64 Protein, L-PLASTIN Protein, LC64P Protein, LPL Protein, PLS2 Protein, cb245 Protein, fj24b12 Protein, wu:fj24b12 Protein, cp64 Protein, l-plastin Protein, lc64p Protein, lpl Protein, pls2 Protein, plastin-2 Protein, AW536232 Protein, D14Ertd310e Protein, LCP-1 Protein, Pls2 Protein, pp65 Protein, lymphocyte cytosolic protein 1 Protein, lymphocyte cytosolic protein 1 (L-plastin) Protein, lymphocyte cytosolic protein 1 (L-plastin) S homeolog Protein, lower matrix protein; involved in immune regulation Protein, LCP1 Protein, lcp1 Protein, lcp1.S Protein, Lcp1 Protein, UL83 Protein
    Background
    Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
    Molecular Weight
    70.1 kDa
    NCBI Accession
    NP_002289
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