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PRELP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

PRELP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729749
  • Target See all PRELP Proteins
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PRELP protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Prolargin / PRELP (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRELP Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
    Alternative Name
    Prolargin,prelp (PRELP Products)
    Synonyms
    7330409J17Rik Protein, SLRR2A Protein, MST161 Protein, MSTP161 Protein, proline arginine-rich end leucine-rich repeat Protein, proline and arginine rich end leucine rich repeat protein Protein, Prelp Protein, PRELP Protein
    Background
    The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
    Molecular Weight
    41.6 kDa
    NCBI Accession
    NP_958505
    Pathways
    Glycosaminoglycan Metabolic Process
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