SIP1 Protein (Myc-DYKDDDDK Tag)
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- Target See all SIP1 (GEMIN2) Proteins
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SIP1 / GEMIN2 (transcript variant alpha) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GEMIN2 Protein
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Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) protein (GST tag)
GEMIN2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) protein (Strep Tag)Crystallography grade GEMIN2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-269) protein (Strep Tag)Crystallography grade GEMIN2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
- Alternative Name
- Sip1,gemin2 (GEMIN2 Products)
- Synonyms
- SIP1 Protein, SIP1-delta Protein, 1700012N19Rik Protein, Sip1 Protein, sip1 Protein, sip1-delta Protein, wu:fc52a05 Protein, zgc:110274 Protein, gem nuclear organelle associated protein 2 Protein, gem (nuclear organelle) associated protein 2 Protein, gem nuclear organelle associated protein 2 S homeolog Protein, GEMIN2 Protein, Gemin2 Protein, gemin2.S Protein, gemin2 Protein
- Background
- This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
- Molecular Weight
- 31.4 kDa
- NCBI Accession
- NP_003607
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
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