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TRIM21 Protein (Myc-DYKDDDDK Tag)

TRIM21 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732675
  • Target See all TRIM21 Proteins
    TRIM21 (Tripartite Motif Containing 21 (TRIM21))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 2
    • 2
    Human
    Source
    • 5
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TRIM21 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human SS-A / Ro52 / TRIM21 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TRIM21 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TRIM21 (Tripartite Motif Containing 21 (TRIM21))
    Alternative Name
    Ss-A,ro52,trim21 (TRIM21 Products)
    Synonyms
    RNF81 Protein, RO52 Protein, SSA Protein, SSA1 Protein, Ro52 Protein, Ssa1 Protein, tripartite motif containing 21 Protein, tripartite motif-containing 21 Protein, TRIM21 Protein, Trim21 Protein
    Background
    This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
    Molecular Weight
    54 kDa
    NCBI Accession
    NP_003132
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