TGFBR2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733517

Product Details

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TGFBR2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TGFBR2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Alternative Name: Tgfbr2 (TGFBR2 Products)

Synonyms: AAT3 Protein, FAA3 Protein, LDS1B Protein, LDS2B Protein, MFS2 Protein, RIIC Protein, TAAD2 Protein, TGFR-2 Protein, TGFbeta-RII Protein, 1110020H15Rik Protein, AU042018 Protein, DNIIR Protein, RIIDN Protein, TBR-II Protein, TbetaR-II Protein, TbetaRII Protein, TGFBR2 Protein, TBETA-RII Protein, TGFBRII Protein, TGF-beta 2 Protein, Tgfbr2T Protein, cb537 Protein, tgfbr2 Protein, wu:fj05c10 Protein, zgc:110498 Protein, transforming growth factor beta receptor 2 Protein, transforming growth factor, beta receptor II Protein, transforming growth factor, beta receptor 2 Protein, transforming growth factor beta receptor 2b Protein, TGFBR2 Protein, Tgfbr2 Protein, tgfbr2b Protein

Background: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Molecular Weight: 62 kDa

NCBI Accession: NP_003233