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TJP3 Protein (Myc-DYKDDDDK Tag)

TJP3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733730
  • Target See all TJP3 Proteins
    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TJP3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Tight junction protein 3 (zona occludens 3) (TJP3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TJP3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
    Abstract
    TJP3 Products
    Synonyms
    cb766 Protein, wu:fj93c08 Protein, zo-3 Protein, zo3 Protein, ZO-3 Protein, ZO3 Protein, tight junction protein 3 Protein, tight junction protein 3 S homeolog Protein, tjp3 Protein, tjp3.S Protein, TJP3 Protein, Tjp3 Protein
    Background
    The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.
    Molecular Weight
    104.6 kDa
    NCBI Accession
    NP_055243
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