TSG101 Protein (DYKDDDDK Tag)

Catalog No. ABIN2734442

Product Details

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Protein Type: Recombinant

Origin: Human

Source: Insect cells (Sf9)

Purification tag / Conjugate: This TSG101 protein is labelled with DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TSG101 (full length, C-term DDK tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Alternative Name: Tsg101 (TSG101 Products)

Synonyms: CG9712 Protein, DmTSG101 Protein, Dmel\\CG9712 Protein, ESCRT-I Protein, Tsg101 Protein, burs Protein, dTSg101 Protein, dTsg101 Protein, dVps23 Protein, ept Protein, tsg101 Protein, vps23 Protein, TSG101 Protein, MGC76193 Protein, TSG10 Protein, VPS23 Protein, AI255943 Protein, CC2 Protein, Rw Protein, zgc:86926 Protein, tumor susceptibility 101 Protein, Tumor susceptibility gene 101 Protein, Tumor Susceptibility Gene homolog Protein, tumor susceptibility gene 101 Protein, tumor susceptibility 101a Protein, tumor susceptibility 101 L homeolog Protein, TSG101 Protein, tsg-101 Protein, tsg101 Protein, Tsg101 Protein, tsg101a Protein, tsg101.L Protein

Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Molecular Weight: 43.8 kDa

NCBI Accession: NP_006283