UBTF Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734925

Product Details

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UBTF protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UBTF / UBF (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Alternative Name: Ubtf,ubf (UBTF Products)

Synonyms: NOR-90 Protein, UBF Protein, UBF-1 Protein, UBF1 Protein, A930005G04Rik Protein, Tcfubf Protein, wu:fj38c10 Protein, si:dz180g5.3 Protein, ubf Protein, Ubtf Protein, ubf1 Protein, xUBF Protein, xUBFbeta2 Protein, UBTF Protein, nor-90 Protein, ubf2 Protein, ubtf Protein, upstream binding transcription factor, RNA polymerase I Protein, upstream binding transcription factor, RNA polymerase I L homeolog Protein, upstream binding transcription factor, RNA polymerase I S homeolog Protein, UBTF Protein, Ubtf Protein, ubtf Protein, ubtf.L Protein, ubtf.S Protein

Background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Molecular Weight: 84.8 kDa

NCBI Accession: NP_001070151