EXO5 Protein (AA 1-373, full length) (His-SUMO Tag)
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- Target See all EXO5 Proteins
- EXO5 (Exonuclease 5 (EXO5))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-373
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EXO5 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MAETREEETV SAEASGFSDL SDSEFLEFLD LEDAQESKAL VNMPGPSSES LGKDDKPISL QNWKRGLDIL SPMERFHLKY LYVTDLATQN WCELQTAYGK ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG ELELAELKTR RRPMLPLEAQ KKKDCFQVSL YKYIFDAMVQ GKVTPASLIH HTKLCLEKPL GPSVLRHAQQ GGFSVKSLGD LMELVFLSLT LSDLPVIDIL KIEYIHQETA TVLGTEIVAF KEKEVRAKVQ HYMAYWMGHR EPQGVDVEEA WKCRTCTYAD ICEWRKGSGV LSSTLAPQVK KAK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product EXO5 Protein
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Exonuclease 5 (EXO5) (AA 1-373) protein (Strep Tag)
Crystallography grade EXO5 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Exonuclease 5 (EXO5) (AA 1-373) protein (Strep Tag)Crystallography grade EXO5 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Exonuclease 5 (EXO5) (AA 1-373), (full length) protein (His-SUMO Tag)EXO5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Exonuclease 5 (EXO5) protein (Myc-DYKDDDDK Tag)EXO5 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- EXO5 (Exonuclease 5 (EXO5))
- Alternative Name
- EXO5 (EXO5 Products)
- Synonyms
- C1orf176 Protein, DEM1 Protein, Exo V Protein, hExo5 Protein, 3110037I16Rik Protein, AV297100 Protein, Dem1 Protein, mExo5 Protein, exonuclease 5 Protein, EXO5 Protein, Exo5 Protein
- Background
- Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting, however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'-directionality activity.
- Molecular Weight
- 57.8 kDa
- UniProt
- Q9H790
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