MYLIP Protein (AA 1-445, full length) (His tag)
-
- Target See all MYLIP Proteins
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-445
-
Origin
- Human
-
Source
- Yeast
- Purification tag / Conjugate
- This MYLIP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS ALLAQTKFGD YNQNTAKYNY EELCAKELSS ATLNSIVAKH KELEGTSQAS AEYQVLQIVS AMENYGIEWH SVRDSEGQKL LIGVGPEGIS ICKDDFSPIN RIAYPVVQMA TQSGKNVYLT VTKESGNSIV LLFKMISTRA ASGLYRAITE THAFYRCDTV TSAVMMQYSR DLKGHLASLF LNENINLGKK YVFDIKRTSK EVYDHARRAL YNAGVVDLVS RNNQSPSHSP LKSSESSMNC SSCEGLSCQQ TRVLQEKLRK LKEAMLCMVC CEEEINSTFC PCGHTVCCES CAAQLQSCPV CRSRVEHVQH VYLPTHTSLL NLTVI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MYLIP Protein
-
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (GST tag)
MYLIP Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (Strep Tag)Crystallography grade MYLIP Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (Strep Tag)Crystallography grade MYLIP Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445), (full length) protein (GST tag)MYLIP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445), (full length) protein (His tag)MYLIP Origin: Human Host: Yeast Recombinant > 90 % SDS
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- Alternative Name
- MYLIP (MYLIP Products)
- Synonyms
- IDOL Protein, MIR Protein, 9430057C20Rik Protein, Mir Protein, mylip Protein, wu:fj36b03 Protein, zgc:55987 Protein, MYLIP Protein, mir Protein, zgc:153767 Protein, myosin regulatory light chain interacting protein Protein, myosin regulatory light chain interacting protein a Protein, myosin regulatory light chain interacting protein L homeolog Protein, myosin regulatory light chain interacting protein b Protein, MYLIP Protein, Mylip Protein, mylipa Protein, mylip.L Protein, mylip Protein, mylipb Protein
- Background
- E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
- Molecular Weight
- 51.9 kDa
- UniProt
- Q8WY64
-
